Open Problem: Finding Replication Origins in Yeast

Replication origins in bacteria vs. yeast

If you think that finding replication origins in bacteria is a complex problem, wait until you analyze replication origins in more complex organisms like yeast or humans, which have hundreds of replication origins. Among various yeast species, the yeast Saccharomyces cerevisiae has the best characterized replication origins. It has approximately 400 different oris, many of which may be used during the replication of any single yeast cell.