Space Efficient Sequence Alignment
Let’s look at a space efficient solution to sequence alignment.
To introduce fitting alignments, we used the example of aligning a 20,000 amino acidlong NRP synthetase from Bacillus brevis against a 600 amino acid-long A-domain from Streptomyces roseosporus. However, you may not be able to construct this alignment on your computer because the memory required to store the dynamic programming matrix is substantial.
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